01 · The question

Can a 30-minute test change decisions at the front door?

~24 hto a laboratory PCR result in this example, while the patient waits for a bed decision.
1 in 3side-room beds held for patients who turn out not to need isolation.
2 of 3patients started on antibiotics before the cause of infection is known.
Faster answers for respiratory infectionsIllustrative data · not real study results

02 · Study design

Who took part

1,240adults with respiratory symptoms assessed
380 excluded: did not meet criteria or declined
860eligible
800randomised
400point-of-care PCR
400standard laboratory PCR
392 analysed
389 analysed
CONSORT-style flow diagramIllustrative data · not real study results

03 · Results

Results in under an hour, and fewer unnecessary antibiotics

Median time to result (hours)

Point of careLaboratory 0.6 h21 h 01224

Effect on outcomes · risk ratio (95% CI)

Antibiotics startedSide-room daysAdmitted 0.78 (0.68–0.90)0.70 (0.58–0.86)0.94 (0.83–1.06) 0.51.0favours point of care
Faster answers for respiratory infectionsIllustrative data · not real study results